Clinical Oncology Interview Questions & Answers
40 NHS interview questions with model answers · 8 free to read
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About this NHS interview question bank
To prepare for a clinical oncology NHS interview, expect questions on palliative and radical radiotherapy at a principles level, IR(ME)R duties, metastatic spinal cord compression, acute oncology, on-treatment review, consent and breaking bad news, and how you work with therapeutic radiographers, physicists and the MDT. Build calm, spoken answers around real cases from your own practice, and know GMC Good Medical Practice, the NHS values and the cancer centre you are applying to before you walk in.
This bank contains 40 original practice questions with first-person model answers written for doctors applying for clinical oncology posts in the NHS, pitched mainly at Clinical Fellow and Specialty Doctor level with a selection that stretches towards consultant-level leadership. It covers radiotherapy planning and consent principles, radiation safety and IR(ME)R, palliative radiotherapy for bone pain and spinal cord compression, side effects and on-treatment review, SACT and chemoradiation, acute oncology, clinical trials, MDT working, safeguarding, confidentiality, audit, teaching and wellbeing. Each question explains what the panel is really assessing, the points you must hit, the mistakes to avoid and the guidance worth reading, so you can practise answers that sound like you rather than a textbook.
What this question bank covers
- Motivation for clinical oncology
- Choosing a cancer centre
- Clinical Fellow and Specialty Doctor roles
- Portfolio pathway and career plans
- NHS values in cancer care
- Cancer waiting times and NHS priorities
- Breaking bad news
- Consent for radiotherapy
- Clinical trials
- IR(ME)R and radiation safety
- Radiotherapy planning and peer review
- Palliative radiotherapy for bone pain
- Metastatic spinal cord compression
- On-treatment review and side effects
- SACT and chemoradiation
- Acute oncology and neutropenic sepsis
- Immunotherapy toxicity
- Working with radiographers, physicists and CNSs
- MDT working
- Safeguarding and mental capacity
- Equality and reasonable adjustments
- Confidentiality and record keeping
- Radiotherapy incidents and Duty of Candour
- Audit, QI and teaching
- Resilience and wellbeing
40 NHS interview questions with full model answers. The first 8 are free to read below. Unlock the remaining 32 for £2.99 (12 months' access).
These are original practice questions written to reflect how NHS interviews are run. They are not leaked or official questions, and Healthcare Interview Prep is independent of the NHS.
Free NHS interview questions and model answers
Question 1: Why do you want to work in clinical oncology?
Motivation question · Motivation
What the interview panel is assessing
The panel wants a genuine, specific reason for choosing clinical oncology rather than medical oncology or general medicine. They are listening for an understanding of what the job really involves, including radiotherapy, SACT, palliative work and difficult conversations, and for realism about its emotional weight.
Model answer
The honest answer is that one patient changed my plans. As a foundation-level doctor I looked after a man in his sixties who came in unable to walk properly because of back pain, and it turned out to be spinal cord compression from prostate cancer he didn't know he had. I was part of the team that got him scanned, started on steroids and referred that night. What struck me was what happened next. The clinical oncologist saw him the following morning, sat on the edge of his bed and explained radiotherapy in a way he could actually follow, and within a few days he was planned and treated. A couple of weeks later his pain had settled enough for him to go home.
That was the first time I understood how much one specialty could hold together. Clinical oncology isn't only radiotherapy. It's systemic treatment, acute oncology, palliative care, long relationships with patients, and some very technical work with physicists and radiographers. I like that mix. I enjoy anatomy and imaging, so the planning side genuinely interests me, but I also find I'm good in the quieter conversations, the ones where someone needs time to understand what's happening to them.
Since then I've tried to test that interest properly. I've spent time in on-treatment review clinics, sat in on planning sessions, and worked on the acute oncology rota. I've seen patients whose cancer we cured and patients whose last few weeks were made more comfortable by a single fraction of radiotherapy. Both feel worthwhile to me.
I won't pretend it's easy. Some days are heavy, and I've learned I need good support and a team around me. But I come away from oncology work feeling I've actually made a difference, and that's why I want to build my career here.
Why this answer works
The answer is grounded in a specific, believable case and shows the candidate understands the breadth of clinical oncology, not just radiotherapy. It demonstrates that interest has been tested through real exposure and shows maturity about the emotional demands.
Key points to include
- A specific moment or patient that shaped your choice
- Understanding that clinical oncology combines radiotherapy, SACT, acute and palliative care
- Evidence you have tested your interest (clinics, planning, acute oncology)
- Realism about the emotional side and how you look after yourself
- What you hope to bring to patients
Common mistakes to avoid
- Talking only about technology and machines, with no patients in the answer
- Confusing clinical oncology with medical oncology
- Saying you want to 'cure cancer' without any realism
- Giving a generic answer that would fit any specialty
NHS values and standards
Compassion; Improving lives; Commitment to quality of care; GMC Good Medical Practice: knowledge, skills and development
Further reading
- GMC Good Medical Practice (2024)
- The Royal College of Radiologists: clinical oncology specialty information
- NHS Constitution for England
Question 2: You are asked to see a patient with painful bone metastases referred for palliative radiotherapy. How would you approach the consultation and treatment decision?
Clinical Scenario question · Clinical Scenario
What the interview panel is assessing
The panel is checking your principles of palliative radiotherapy: careful assessment, ruling out complications such as cord compression or fracture risk, choosing a simple and effective fractionation, and consenting properly. They also want to see that the patient's goals and comfort drive the decision.
Model answer
I'd start before I meet the patient by reading the referral, the imaging and the most recent clinic letters, so I know the primary, what systemic treatment they're on and what the MDT has said. With bone metastases I want to know exactly where the pain is coming from and whether the imaging actually matches it.
In the room I'd take a proper pain history: where it is, how it affects sleep and walking, what analgesia they're taking and whether it's working. Then I'd be specifically looking for red flags. Any back pain that's new, band-like or worse lying flat, any weakness, numbness or change in bladder or bowel function makes me think about cord compression, and that changes the urgency completely. I'd also think about fracture risk, especially in a weight-bearing long bone, because a lesion that looks at risk of breaking may need an orthopaedic opinion before radiotherapy rather than instead of it.
If it's uncomplicated bone pain, the evidence supports a single fraction being as effective for pain relief as longer courses, with a slightly higher chance of needing retreatment later. For most patients one visit is a real advantage, particularly if they're frail or travelling a long way. I'd plan in line with our departmental protocols and check with my consultant if anything is unusual, such as previous radiotherapy to the same area.
Consent would cover what we hope to achieve, which is pain relief rather than cure, how long it takes to work, and the common side effects, including a temporary pain flare and site-specific effects such as nausea or diarrhoea depending on the area treated. I'd make sure their analgesia is optimised in the meantime, think about referral to the palliative care team if symptoms are complex, and let the GP and the clinical nurse specialist know the plan.
Most of all I'd ask the patient what matters to them. Sometimes the right decision is a quick single fraction so they can get on with a family event. That conversation shapes everything else.
Why this answer works
This answer follows a safe clinical sequence: prepare, assess, exclude cord compression and impending fracture, then choose a proportionate treatment. It reflects accepted practice on single-fraction treatment without overstating details, and it keeps the patient's priorities and symptom control central.
Key points to include
- Review imaging, history and MDT plan first
- Screen for MSCC symptoms and fracture risk, including orthopaedic input
- Single fraction is effective for uncomplicated bone pain; follow departmental protocols
- Consent covering aim, timing, pain flare and site-specific effects
- Optimise analgesia and involve palliative care and the CNS
Common mistakes to avoid
- Missing red flags for spinal cord compression
- Defaulting to long fractionation without considering patient burden
- Forgetting to mention analgesia and pain flare
- Presenting palliative radiotherapy as potentially curative
NHS values and standards
Compassion; Commitment to quality of care; Improving lives; GMC Good Medical Practice: patients, partnership and communication
Further reading
- The Royal College of Radiologists: Radiotherapy dose fractionation guidance
- NICE guideline on spinal metastases and metastatic spinal cord compression
- GMC Decision making and consent (2020)
- Local radiotherapy department protocols
Question 3: Tell me how you would break the news to a patient that their cancer has progressed despite treatment.
Communication question · Communication
What the interview panel is assessing
The panel wants to see a structured, compassionate approach to breaking bad news that you can actually use in clinic. They are listening for preparation, finding out what the patient already knows, honest information delivered at their pace, and a clear plan and support afterwards.
Model answer
I'd prepare first. I'd read the scan report myself and look at the images with a radiologist or my consultant if I'm unsure, and I'd know what the realistic options are before I go in, whether that's a change of systemic treatment, palliative radiotherapy, a trial or a focus on comfort. I'd ask the clinical nurse specialist to join me if possible, book a quiet room, and hand my bleep to a colleague.
I remember a woman with lung cancer whose scan after several cycles of treatment showed new liver disease. I started by asking how she'd been feeling and what she thought the scan might show. She said she'd been more tired and was worried. That told me she was partly expecting it, so I gave a warning shot: 'I'm afraid the scan hasn't shown what we'd hoped.' Then I paused.
I explained in plain words that the cancer had grown and spread to the liver, and that the treatment wasn't controlling it. I didn't rush to fill the silence. She cried, and her daughter held her hand. When she was ready, she asked whether this meant she was dying. I answered honestly that we couldn't cure the cancer, but that there were still things we could do to try to control it and keep her comfortable, and that we'd talk about time if and when she wanted to.
We then talked through options in outline and agreed not to make any decisions that day. The specialist nurse arranged to phone her later in the week, I gave her a contact number, and I documented the conversation carefully, including what she'd been told and what she wanted to know, so the next clinician didn't have to guess. I also wrote to her GP the same day.
What I've learned is that the words matter less than the pace. Checking understanding, allowing silence and making sure the patient leaves with a plan and a named person to contact are what make it bearable.
Why this answer works
The answer follows a recognised framework such as SPIKES without sounding mechanical, and uses a realistic example to show it in action. It balances honesty with hope, includes the CNS and GP, and highlights documentation and follow-up.
Key points to include
- Prepare: know the results, the options and have the right people present
- Find out what the patient knows and wants to know
- Warning shot, plain language, then silence
- Honest answers without removing all hope
- Clear plan, contact details, documentation and GP letter
Common mistakes to avoid
- Rushing into treatment options before the news has sunk in
- Using jargon such as 'progressive disease' without explanation
- Giving a prognosis in exact months when not asked or not known
- Forgetting follow-up, documentation or the specialist nurse
NHS values and standards
Compassion; Respect and dignity; Working together for patients; GMC Good Medical Practice: communication and partnership
Further reading
- GMC Good Medical Practice (2024)
- GMC Decision making and consent (2020)
- NICE guideline on improving supportive and palliative care for adults with cancer
- SPIKES protocol for breaking bad news
Question 4: What are your responsibilities under IR(ME)R as a doctor working in clinical oncology?
Technical question · Technical
What the interview panel is assessing
The panel wants to know that you understand the legal framework for medical exposures to ionising radiation and the duty holder roles. They are looking for a practical, safe understanding of justification, entitlement, pregnancy checks and incident reporting, not a recited regulation.
Model answer
The Ionising Radiation (Medical Exposure) Regulations 2017, IR(ME)R, set out who is responsible for each step of a medical exposure. Northern Ireland has its own equivalent regulations, but the principles are the same. The key idea is that every exposure must be justified and optimised, and that everyone involved has a defined duty holder role and is entitled by the employer to carry it out.
The duty holders are the employer, the referrer, the practitioner and the operator, with the medical physics expert advising. In radiotherapy, a clinical oncologist will often act as referrer and practitioner, because we decide that treatment is indicated and we justify the exposure. Practical parts of the process, such as outlining target volumes or signing a prescription, are operator functions. What matters to me is that I only carry out the roles I've been formally entitled to do in that department, and as a new Clinical Fellow I'd expect my scope to be defined clearly and to grow with training and sign-off.
Justification means I'm satisfied the benefit outweighs the risk for that individual, considering alternatives and previous radiotherapy. Optimisation is a shared job with physics and radiographers, keeping dose to normal tissues as low as reasonably practicable while treating the target properly.
Then there are the specific checks. I make sure the correct patient is identified, that pregnancy status has been established for anyone of childbearing potential in line with the employer's procedures, and that consent and the prescription are complete and match. I also apply the same thinking to the imaging I request, such as planning CT scans and on-treatment imaging, because those are exposures too.
Finally, if something goes wrong, I report it through the local incident system straight away. The employer has a duty to notify the regulator of significant accidental or unintended exposures, which in England is the CQC, with equivalent bodies in the other nations. I'd always ask if I was unsure what my entitlement covered, because that's exactly where errors happen.
Why this answer works
The answer names the regulations accurately, explains the duty holder roles in a radiotherapy context, and links them to everyday actions like checking identity, pregnancy and prescriptions. It shows awareness of entitlement and scope at a junior grade and of regulator notification.
Key points to include
- Duty holders: employer, referrer, practitioner, operator, with medical physics expert advice
- Justification and optimisation of every exposure
- Only act within your formal entitlement
- Identity, pregnancy checks, consent and prescription accuracy
- Incident reporting and regulator notification for significant events
Common mistakes to avoid
- Confusing IR(ME)R with the Ionising Radiations Regulations that protect staff
- Forgetting that planning and verification imaging are exposures too
- Implying you can do any role without entitlement
- Not knowing who regulates IR(ME)R in your nation
NHS values and standards
Commitment to quality of care; Everyone counts; GMC Good Medical Practice: safety and quality
Further reading
- Ionising Radiation (Medical Exposure) Regulations 2017
- Ionising Radiation (Medical Exposure) Regulations (Northern Ireland) 2018
- Employer's IR(ME)R procedures for your department
- CQC guidance on IR(ME)R
- The Royal College of Radiologists guidance on radiotherapy
Question 5: You are on call and receive a phone call about a patient with known breast cancer who has new back pain and leg weakness. What would you do?
Clinical Scenario question · Clinical Scenario
What the interview panel is assessing
This tests recognition and urgent management of suspected metastatic spinal cord compression. The panel wants safe, time-critical actions: immediate assessment, urgent MRI, appropriate steroids and spinal precautions, early involvement of the MSCC coordinator and spinal team, and clear escalation.
Model answer
This is suspected metastatic spinal cord compression until proven otherwise, and it's an emergency because the neurological outcome depends on how quickly we act. The single most important predictor of whether someone walks after treatment is whether they're walking before it.
First I'd get the key facts: where the patient is, how long the weakness has been there, whether it's progressing, and whether there's any numbness, a sensory level, urinary retention or bowel change. If they're at home or in another hospital, I'd advise urgent assessment in an emergency department. If they're on our ward, I'd go and see them myself straight away.
On examination I'd do a full neurological assessment and document it clearly, because that baseline matters. I'd check for a palpable bladder. Until spinal stability is assessed, I'd follow local guidance on positioning and log rolling, especially if the pain is severe or mechanical.
Then I'd arrange an urgent MRI of the whole spine, because there can be more than one level involved. I'd contact the MSCC coordinator, as most cancer centres have a single point of contact. I'd start dexamethasone in line with our local MSCC protocol if there's a neurological deficit, with gastric protection and blood glucose monitoring, and make sure they have adequate analgesia.
Once the MRI confirms compression, the decision about surgery or radiotherapy is made quickly with the spinal surgical team, the oncology consultant and the patient. Factors include spinal stability, the patient's overall condition and prognosis, and how radiosensitive the tumour is. If radiotherapy is the plan, I'd work with my consultant and the radiotherapy team to get them planned and treated as soon as possible.
Throughout, I'd involve my consultant early rather than wait for the scan, keep the patient and family informed, and remember the longer-term needs too: thromboprophylaxis, pressure care, bladder care and rehabilitation.
Why this answer works
The answer treats the situation as an emergency, follows a clear sequence and reflects the principles of national MSCC guidance without quoting doses or timescales it cannot be certain of. It shows early senior involvement, multidisciplinary decision-making and attention to holistic care.
Key points to include
- Recognise suspected MSCC as an emergency
- Full neurological examination, documented as a baseline
- Urgent whole-spine MRI and contact the MSCC coordinator
- Steroids per local protocol, analgesia and spinal precautions as advised
- Early consultant and spinal surgical involvement; surgery versus radiotherapy decision
Common mistakes to avoid
- Waiting for the MRI before escalating to a senior
- Imaging only the painful part of the spine
- Forgetting bladder assessment and documentation of baseline neurology
- Ignoring rehabilitation, VTE and pressure area care
NHS values and standards
Commitment to quality of care; Compassion; Working together for patients; GMC Good Medical Practice: safety and quality
Further reading
- NICE guideline on spinal metastases and metastatic spinal cord compression
- Local acute oncology and MSCC pathway
- UKONS acute oncology guidance
- GMC Good Medical Practice (2024)
Question 6: Which of the NHS values matters most to you in clinical oncology, and how have you shown it?
NHS Values question · NHS Values
What the interview panel is assessing
The panel is checking that you know the NHS values and can link one convincingly to real behaviour in cancer care. They want an example of what you did, not a definition, and some understanding of why that value has particular weight in oncology.
Model answer
The six NHS values are working together for patients, respect and dignity, commitment to quality of care, compassion, improving lives, and everyone counts. In oncology the one I come back to most is respect and dignity, because patients with cancer can very quickly lose control over their own lives. Their week is built around appointments, they're examined by lots of different people, and they can start to feel like a diagnosis rather than a person.
I saw this with a man in his seventies having a course of radiotherapy for head and neck cancer. He'd been a teacher, quite private, and by the third week he was struggling to eat and losing weight. In the review clinic he was quite short with me. Rather than going straight through my checklist of side effects, I asked him what had been the hardest part. He told me he hated being weighed in the corridor and being talked about as 'the feeding tube conversation' before anyone had asked him what he wanted.
That was fair. So I slowed down. I explained honestly why the dietitians were worried and what a feeding tube would and wouldn't mean for him, and I asked what he was worried about. It turned out he thought a tube meant he'd never eat normally again. Once we'd talked that through with the dietitian, he agreed to it on his own terms. I also mentioned to the radiographers and the clinic nurse that we could weigh him somewhere more private, and they changed it straight away.
It was a small thing, but it reminded me that respect isn't just being polite. It's making sure people still have a say in what happens to them, even when they're unwell and the decisions are medical.
Why this answer works
The answer names all six values accurately, then chooses one and shows it through a specific, believable oncology example. It demonstrates listening, shared decision-making and practical changes, and connects dignity to autonomy.
Key points to include
- Name the NHS values accurately
- Pick one and explain why it matters in oncology
- A specific example of your own behaviour
- Show the patient's voice shaping the outcome
- Reflect on what you learned
Common mistakes to avoid
- Listing values with no example
- Choosing a value but describing a team achievement with no personal role
- An example that isn't from cancer or acute care when the panel wants role relevance
- Sounding scripted or preachy
NHS values and standards
Respect and dignity; Compassion; Working together for patients; GMC Good Medical Practice
Further reading
- NHS Constitution for England
- GMC Good Medical Practice (2024)
- GMC Decision making and consent (2020)
Question 7: How do you work with therapeutic radiographers and medical physicists, and can you give an example?
Teamwork question · Teamwork
What the interview panel is assessing
The panel wants evidence that you value the expertise of therapeutic radiographers, dosimetrists and physicists, communicate clearly with them, and respond well when they raise concerns. Radiotherapy is only safe when the whole team feels able to speak up.
Model answer
Radiotherapy is one of the most team-based things a doctor does. I might outline a target and sign a prescription, but the plan is produced by dosimetrists and physicists, checked independently, and then delivered every day by therapeutic radiographers who see the patient far more often than I do. If I treat any of them as a service rather than as colleagues, the patient is less safe.
One example stays with me. I'd outlined a target volume for a palliative pelvic treatment and the plan came back from planning with a note from the physicist. The dose to a nearby area of bowel was higher than she'd expect for that technique, and she asked whether my volume was meant to extend that far. When I looked again with fresh eyes, I'd included more of a nodal area than the clinical picture justified. I thanked her, discussed it with my consultant, and we tightened the volume. The revised plan was better for the patient.
Another time, a radiographer bleeped me because a patient on treatment looked much more breathless than at the start. It would have been easy to say 'I'll see him in review clinic on Thursday', but I went down. His oxygen saturation was low and he needed admission. She was right to flag it.
What I try to do day to day is simple. I answer bleeps from the treatment unit promptly, I make sure my prescriptions and notes are clear and complete so nobody has to chase me, and I ask radiographers what they're seeing because they often notice a skin reaction or a change in mood before anyone else. I also spend time learning what they do. Sitting in on a planning session and a treatment set-up taught me more about the process than any lecture.
The main thing I've learned is that a query from physics or radiography is a safety net, not a criticism.
Why this answer works
The answer shows real understanding of the radiotherapy pathway and the roles in it, with two specific examples where listening to colleagues improved safety. It frames challenge from other professionals positively and lists concrete everyday behaviours.
Key points to include
- Understand each professional's role in the radiotherapy pathway
- Example of acting on a physics or radiography query
- Respond promptly and see patients when radiographers raise concerns
- Clear, complete prescriptions and documentation
- Treat challenge as a safety net
Common mistakes to avoid
- Describing radiographers or physicists as people who 'carry out the doctor's plan'
- Getting defensive when a query is raised
- Vague teamwork answers with no radiotherapy content
- Forgetting the patient in a teamwork example
NHS values and standards
Working together for patients; Commitment to quality of care; Respect and dignity; GMC Good Medical Practice: working collaboratively with colleagues
Further reading
- GMC Good Medical Practice (2024)
- Ionising Radiation (Medical Exposure) Regulations 2017
- Society of Radiographers and Institute of Physics and Engineering in Medicine professional guidance
- Towards Safer Radiotherapy (joint professional guidance)
Question 8: Tell us about a time you made a mistake or were involved in a near miss. What happened and what did you learn?
Patient Safety question · Patient Safety
What the interview panel is assessing
The panel wants honesty, ownership and learning. They are looking for a real but appropriate example, prompt action to keep the patient safe, escalation and incident reporting, and evidence that you changed your practice and helped the system improve.
Model answer
As a junior doctor on an oncology ward I prescribed a patient's regular medications on admission and missed that she'd stopped one of her oral anticancer tablets a week earlier on her oncologist's advice. I'd copied it from an older clinic letter. The pharmacist picked it up during medicines reconciliation the next morning, before any dose was given.
My first feeling was a horrible jolt, because oral SACT isn't something you get casually wrong. I went straight to the pharmacist, thanked her, checked the most recent letter and confirmed with the patient what she was actually taking. I amended the chart, told my registrar and completed an incident report, even though no harm had happened, because a near miss is still useful learning.
I also spoke to the patient. I explained there'd been an error on her drug chart that had been corrected before she received anything and apologised. She appreciated being told, and it felt like the right thing to do.
When I reflected afterwards, the problem wasn't just my lapse. The latest letter wasn't easy to find, and oral anticancer medicines on that ward were being prescribed on the general chart rather than through the SACT prescribing system. I raised that at the ward's safety meeting, and the team agreed a simple rule that oral SACT on admission is held until confirmed by the oncology team or pharmacy against the electronic SACT record. That later became part of a short teaching session for new doctors.
Since then I never rely on a single source for anticancer medicines. I check the electronic SACT record, ask the patient, and involve pharmacy early. I also wrote it up as a reflection in my portfolio and discussed it with my educational supervisor. I'd much rather be the doctor who reports a near miss than one who hides it.
Why this answer works
The answer is honest about a real, relevant error, shows immediate safe action and open communication with the patient, and goes beyond personal learning to a system fix. It shows maturity and an understanding of a just, learning culture.
Key points to include
- A real, proportionate example with clear ownership
- Immediate action to keep the patient safe
- Escalation, incident reporting and openness with the patient
- Systems learning, not just 'I'll be more careful'
- Reflection and discussion with a supervisor
Common mistakes to avoid
- Choosing a 'mistake' that is really a strength
- Blaming others or the system without owning your part
- Not mentioning incident reporting or telling the patient
- Choosing an example so serious it raises fitness to practise concerns without showing learning
NHS values and standards
Commitment to quality of care; Working together for patients; GMC Good Medical Practice: openness and honesty when things go wrong
Further reading
- GMC and NMC joint guidance: Openness and honesty when things go wrong (professional duty of candour)
- Patient Safety Incident Response Framework (PSIRF), England
- GMC Good Medical Practice (2024)
- Local SACT and oral anticancer medicines policy
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To prepare for a clinical oncology NHS interview, expect questions on palliative and radical radiotherapy at a principles level, IR(ME)R duties, metastatic spinal cord compression, acute oncology, on-treatment review, consent and breaking bad news, and how you work with therapeutic radiographers, physicists and the MDT. Build calm, spoken answers around real cases from your own practice, and know GMC Good Medical Practice, the NHS values and the cancer centre you are applying to before you walk in.